Oracle Databases are a target of cyber-attacks by hackers looking to obtain sensitive data such as credit card numbers and personally identifiable information used in identify theft. Even though databases are not externally accessible, they are still a target as most cyber-attacks penetrate the network perimeter and look for high value targets within your internal network. Based on lessons learned from recent high-profile cyber-attacks, a framework and techniques for detection and prevention of these cyber-attacks against database will be presented.